Pulmonary Artery Denervation
نویسندگان
چکیده
منابع مشابه
Pulmonary Artery Denervation for Pulmonary Artery Hypertension.
W hile the seminal advance in the treatment of pulmonary artery hypertension (PAH) over the past 2 decades has been pharmacological targeting of dysfunctional endothelium-derived pathways that contribute to the characteristic vascular remodeling of this condition irrespective of etiology (1), several novel interventional techniques have also been useful in selected patients. Atrial septostomy, ...
متن کاملPulmonary Artery Denervation to Treat Pulmonary Arterial Hypertension
Methods O f a total of 21 patients with IPAH, 13 patients received the PADN procedure, and the other 8 patients who refused the PADN procedure were assigned to the control group. PADN was performed at the bifurcation of the main PA, and at the ostial right and left PA. Serial echocardiography, right heart catheterization, and a 6-min walk test (6MWT) were performed. The primary endpoints were t...
متن کاملPulmonary Artery Denervation Reduces Pulmonary Artery Pressure and Induces Histological Changes in an Acute Porcine Model of Pulmonary Hypertension
BACKGROUND Pulmonary arterial hypertension is a devastating disease with high morbidity and mortality and limited treatment options. Recent studies have shown that pulmonary artery denervation improves pulmonary hemodynamics in an experimental model and in an early clinical trial. We aimed to evaluate the nerve distribution around the pulmonary artery, to determine the effect of radiofrequency ...
متن کاملPercutaneous pulmonary artery denervation completely abolishes experimental pulmonary arterial hypertension in vivo.
AIMS The study sought to assess the effect of percutaneous pulmonary artery denervation (PADN) on balloon-occlusion-induced acute pulmonary arterial hypertension (PAH) in vivo. The PADN is a minimally invasive and endovascular catheter-based interventional therapy using radiofrequency ablation to abolish the pulmonary arterial baroreceptors to pressure response. METHODS AND RESULTS To examine...
متن کاملPericardial effusion is correlated with clinical outcome after pulmonary artery denervation for pulmonary arterial hypertension
OBJECTIVES Pericardial effusion (PE) is correlated with outcomes in patients with pulmonary arterial hypertension (PAH). Pulmonary artery denervation (PADN) was used for treatment of PAH. The present study aimed to analyze the prognostic value of PE for outcomes after PADN in patients with WHO Group I, Group II and Group IV PAH. RESULTS PE, frequently seen in patients with connective tissue d...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Interventions
سال: 2019
ISSN: 1936-8798
DOI: 10.1016/j.jcin.2019.01.220